- Description
CSB VLPs: Our virus-like particles display FULL-LENGTH membrane proteins in a NATIVE mammalian lipid bilayer, preserving the conformational structure. Each preparation is SPECIFIC to your target, providing a stable antigen for immunization, display selection, screening, and SPR/BLI characterization.
| Target | PD-1 |
| Target Aliases | PD1, PDCD1, CD279, HSLE1, SLEB2, HPD-1, HPD-L |
Stable for 12 months from date of receipt at -80°C or lower. Avoid repeated freeze-thaw cycles.
PD-1 is single-pass transmembrane protein and an immune-inhibitory receptor on activated T-cells. PD-1 plays a role in regulation of T-cell functions and is important for protecting against autoimmunity. PD-1 can also inhibit anti-microbial and anti-tumor immunity, and is expressed in various tumors, including melanomas.