- Description
CSB VLPs: Our virus-like particles display FULL-LENGTH membrane proteins in a NATIVE mammalian lipid bilayer, preserving the conformational structure. Each preparation is SPECIFIC to your target, providing a stable antigen for immunization, display selection, screening, and SPR/BLI characterization.
| Target | CLDN3 |
| Target Aliases | C7orf1, CPE-R2, CPETR2, HRVP1, RVP1 |
Stable for 12 months from date of receipt at -80°C or lower. Avoid repeated freeze-thaw cycles.
Claudin-3 is a member of the claudin family of tight junction proteins encoded by the CLDN3 gene. It is an integral membrane protein with four transmembrane helices, two extracellular loops, and cytoplasmic N- and C-terminal tails that contribute to tight junction strand formation and cell-cell barrier organization. Claudin-3 is expressed in a range of epithelial tissues where it helps regulate paracellular permeability, maintenance of polarity, and intercellular adhesion. Its localization at tight junctions supports epithelial barrier integrity in organs such as gastrointestinal and reproductive tissues.
