- Description
CSB VLPs: Our virus-like particles display FULL-LENGTH membrane proteins in a NATIVE mammalian lipid bilayer, preserving the conformational structure. Each preparation is SPECIFIC to your target, providing a stable antigen for immunization, display selection, screening, and SPR/BLI characterization.
| Target | CLDN2 |
| Target Aliases | OAZON, claudin-2 |
Stable for 12 months from date of receipt at -80°C or lower. Avoid repeated freeze-thaw cycles.
Claudin-2 is a member of the claudin family of tight junction proteins encoded by the CLDN2 gene. It is an integral membrane protein with four transmembrane helices, two extracellular loops, and cytoplasmic N- and C-terminal tails that participate in tight junction strand assembly. Claudin-2 is expressed in epithelial tissues including kidney and intestine, where it forms cation-selective paracellular channels that influence permeability to small ions and water. Its distribution contributes to regulation of epithelial barrier properties and transepithelial transport.
