- Description
CSB VLPs: Our virus-like particles display FULL-LENGTH membrane proteins in a NATIVE mammalian lipid bilayer, preserving the conformational structure. Each preparation is SPECIFIC to your target, providing a stable antigen for immunization, display selection, screening, and SPR/BLI characterization.
| Target | CLDN1 |
| Target Aliases | CLD1, ILVASC, SEMP1 |
Stable for 12 months from date of receipt at -80°C or lower. Avoid repeated freeze-thaw cycles.
Claudin-1 is a member of the claudin family of tight junction proteins encoded by the CLDN1 gene. It is an integral membrane protein with four transmembrane helices, two extracellular loops, and cytoplasmic N- and C-terminal tails that contribute to tight junction strand formation. Claudin-1 is expressed in epithelial and endothelial tissues where it regulates paracellular barrier properties, cell polarity, and intercellular adhesion. It is particularly abundant in skin and other barrier-forming epithelia and is required for normal epidermal barrier function.
