- Description
CSB VLPs: Our virus-like particles display FULL-LENGTH membrane proteins in a NATIVE mammalian lipid bilayer, preserving the conformational structure. Each preparation is SPECIFIC to your target, providing a stable antigen for immunization, display selection, screening, and SPR/BLI characterization.
| Target | CD27 |
| Target Aliases | CD27 antigen, TNFRSF7, T-cell activation antigen CD27, S152, Tp55 |
Stable for 12 months from date of receipt at -80°C or lower. Avoid repeated freeze-thaw cycles.
CD27 is a member of the tumor necrosis factor receptor superfamily encoded by the CD27 gene. It is a type I transmembrane glycoprotein with extracellular cysteine-rich domains characteristic of TNF receptor family members and an intracellular region that mediates signal transduction through TRAF adaptor proteins. CD27 is expressed mainly on T cells, memory B cells, subsets of NK cells, and hematopoietic progenitors, where interaction with its ligand CD70 promotes lymphocyte activation, survival, proliferation, and differentiation. Surface expression can be regulated through activation-dependent shedding and internalization.
