- Description
CSB VLPs: Our virus-like particles display FULL-LENGTH membrane proteins in a NATIVE mammalian lipid bilayer, preserving the conformational structure. Each preparation is SPECIFIC to your target, providing a stable antigen for immunization, display selection, screening, and SPR/BLI characterization.
| Target | CD19 |
| Target Aliases | B4, CVID3 |
Stable for 12 months from date of receipt at -80°C or lower. Avoid repeated freeze-thaw cycles.
CD19 is a B-lymphocyte surface glycoprotein belonging to the immunoglobulin superfamily encoded by the CD19 gene. It is a single-pass type I transmembrane protein with two extracellular immunoglobulin-like domains and a cytoplasmic tail containing signaling motifs that recruit intracellular adaptors. CD19 is expressed throughout most stages of B-cell development and functions as a coreceptor that amplifies signaling through the B-cell receptor complex, contributing to B-cell activation, proliferation, and differentiation. Expression is largely restricted to normal and malignant B-lineage cells.
