- Description
CSB VLPs: Our virus-like particles display FULL-LENGTH membrane proteins in a NATIVE mammalian lipid bilayer, preserving the conformational structure. Each preparation is SPECIFIC to your target, providing a stable antigen for immunization, display selection, screening, and SPR/BLI characterization.
| Target | CD117 |
| Target Aliases | C-Kit, CD117, MASTC, PBT, SCFR |
Stable for 12 months from date of receipt at -80°C or lower. Avoid repeated freeze-thaw cycles.
CD117 (C-Kit) is a receptor tyrosine kinase that plays a critical role in hematopoiesis, melanogenesis, and gametogenesis by binding its ligand, stem cell factor (SCF). It is predominantly expressed in hematopoietic stem cells, mast cells, germ cells, and melanocytes. CD117 is widely studied for its involvement in various cancers, particularly gastrointestinal stromal tumors and certain leukemias, making it a significant target in cancer research and therapy development. Other names: C-Kit, MASTC, PBT, SCFR For more details, see: - [UniProt: P10721 (Human)](https://www.uniprot.org/uniprot/P10721) - [NCBI Gene: 3815 (Human)](https://www.ncbi.nlm.nih.gov/gene/3815) - [Human Protein Atlas: ENSG00000157404 (Human)](https://www.proteinatlas.org/ENSG00000157404) - [GeneCards: CD117 (Human)](https://www.genecards.org/cgi-bin/carddisp.pl?gene=KIT) - [Ensembl Gene: ENSG00000157404 (Human)](https://www.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000157404)
