- Description
CSB VLPs: Our virus-like particles display FULL-LENGTH membrane proteins in a NATIVE mammalian lipid bilayer, preserving the conformational structure. Each preparation is SPECIFIC to your target, providing a stable antigen for immunization, display selection, screening, and SPR/BLI characterization.
| Target | CCR2b |
| Target Aliases | CC-CKR-2, CCR-2, CCR2A, CCR2B, CD192, CKR2, CKR2A, CKR2B, CMKBR2, MCP-1-R, PCLUD |
Stable for 12 months from date of receipt at -80°C or lower. Avoid repeated freeze-thaw cycles.
CCR2b is an alternatively spliced isoform of the C-C chemokine receptor CCR2 and belongs to the class A G protein-coupled receptor family. The human protein is a seven-pass transmembrane receptor with an extracellular N-terminus and an intracellular C-terminus that differs from CCR2a. CCR2b binds C-C chemokines, including CCL2, and activates heterotrimeric G-protein signaling involved in chemotaxis and cellular migration.
