- Description
CSB VLPs: Our virus-like particles display FULL-LENGTH membrane proteins in a NATIVE mammalian lipid bilayer, preserving the conformational structure. Each preparation is SPECIFIC to your target, providing a stable antigen for immunization, display selection, screening, and SPR/BLI characterization.
| Target | ADRA2A |
| Target Aliases | ADRA2, ADRA2R, ADRAR, ALPHA2AAR, FPLD8, Alpha-2 adrenergic receptor subtype A |
Stable for 12 months from date of receipt at -80°C or lower. Avoid repeated freeze-thaw cycles.
Alpha-2A adrenergic receptor is a member of the rhodopsin-like class A G protein-coupled receptor family and responds to the catecholamines epinephrine and norepinephrine. The human receptor is a 450-amino-acid integral membrane protein containing seven transmembrane helices, an extracellular amino terminus, and an intracellular carboxyl terminus. ADRA2A primarily couples to inhibitory G proteins of the Gi/Go family, reducing adenylyl cyclase activity and intracellular cyclic AMP levels. Its experimentally supported functions include regulation of neurotransmitter release and modulation of physiological responses mediated by adrenergic signaling.
