- Description
CSB VeRSaMAbs:
We produce and validate all our monoclonal antibodies in-house so that you can confidently choose the right antibody for your assay. All antibodies are VALIDATED for common applications, RECOMBINANT for batch-to-batch consistency, and SPECIFIC in binding to only your target.
| Target | PMP22 |
| Target Aliases | Peripheral Myelin Protein 22, Gas3, HMSNIA, Sp110, HNPP |
| Isotype | IgG2a |
| Species Reactivity | Human (Others untested) |
| Concentration | 1 mg/ml |
Stable for 12 months from date of receipt when stored at 4°C. Avoid repeated freeze-thaw cycles.
Peripheral myelin protein 22 is a member of the PMP-22/EMP/MP20/Claudin superfamily of tetra-span integral membrane proteins. The protein contains four transmembrane helices with two extracellular loops and cytoplasmic N- and C-termini and is localized to compact myelin in the peripheral nervous system. PMP22 is produced by Schwann cells and contributes to myelin sheath structure and stability. Expression data indicate predominant enrichment in peripheral nerve tissue.