- Description
CSB VeRSaMAbs:
We produce and validate all our monoclonal antibodies in-house so that you can confidently choose the right antibody for your assay. All antibodies are VALIDATED for common applications, RECOMBINANT for batch-to-batch consistency, and SPECIFIC in binding to only your target.
| Target | PERP |
| Target Aliases | PIGPC1, TP53 apoptosis effector, P53 Apoptosis Effector Related To PMP22, KRTCAP1, KCP1, THW |
| Isotype | IgG2a |
| Species Reactivity | Human (Others untested) |
| Concentration | 1 mg/ml |
Stable for 12 months from date of receipt when stored at 4°C. Avoid repeated freeze-thaw cycles.
PERP apoptosis effector is a tetra-span integral membrane protein belonging to the PMP-22/EMP/MP20/Claudin superfamily. The protein contains four transmembrane helices with cytoplasmic N- and C-termini and localizes to the plasma membrane, where it associates with desmosomal complexes. PERP is a transcriptional target of TP53 and TP63 and contributes to epithelial cell–cell adhesion and regulation of apoptosis. Expression is detected in epithelial tissues, consistent with its role in maintaining desmosome integrity.
