Flow Cytometry, Extracellular: HEK-293F cells transiently transfected with human MRGPRX4 were stained with MRGPRX4 Monoclonal Antibody (CSB0176) (green) or isotype control antibody (gray), followed by AlexaFluor 647- conjugated anti-Mouse IgG secondary antibody. HEK-293F cells transiently transfected with an empty control vector were also stained with MRGPRX4 Monoclonal Antibody (CSB0176) (blue).

Flow Cytometry, Extracellular: HEK-293F cells transiently transfected with human MRGPRX4 were stained with MRGPRX4 Monoclonal Antibody (CSB0176) (green) or isotype control antibody (gray), followed by AlexaFluor 647- conjugated anti-Mouse IgG secondary antibody. HEK-293F cells transiently transfected with an empty control vector were also stained with MRGPRX4 Monoclonal Antibody (CSB0176) (blue).

MRGPRX4 MAb - CSB0176

Catalog #: CSB0176
Applications: FC   IF   ICC   ELISA   WB  
Isotype: IgG2a
Reactivity: Human (Others untested)
Extracellular epitope: Yes
Concentration: 1 mg/ml
Size: 100 µg
Fixative Compatibility: Paraformaldehyde (4%)
Detergent Compatibility: Triton X-100 (0.1%)
Technical Data Sheet
Safety Data Sheet
$475.00
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  • Description
Description

CSB VeRSaMAbs:
We produce and validate all our monoclonal antibodies in-house so that you can confidently choose the right antibody for your assay. All antibodies are VALIDATED for common applications, RECOMBINANT for batch-to-batch consistency, and SPECIFIC in binding to only your target.

Target MRGPRX4
Target Aliases MRGX4, Mas-Related G-Protein Coupled Receptor Member X4, MAS-Related GPR, Member X4, SNSR6
Isotype IgG2a
Species Reactivity Human (Others untested)
Concentration 1 mg/ml

Stable for 12 months from date of receipt when stored at 4°C. Avoid repeated freeze-thaw cycles.

Mas-related G-protein coupled receptor member X4 (MRGPRX4) is a member of the class A rhodopsin-like G protein-coupled receptor (GPCR) family, encoded by the MRGPRX4 gene. It is part of the MAS-related GPCR subfamily and is localized to the cell membrane. MRGPRX4 has been shown to act as a receptor for bile acids and triggers intracellular calcium release through Gq/11-mediated signaling. Its function is supported by data from heterologous expression systems, and its physiological role remains incompletely characterized.

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