- Description
CSB VeRSaMAbs:
We produce and validate all our monoclonal antibodies in-house so that you can confidently choose the right antibody for your assay. All antibodies are VALIDATED for common applications, RECOMBINANT for batch-to-batch consistency, and SPECIFIC in binding to only your target.
| Target | LILRB3 |
| Target Aliases | LIR-3, ILT5, LIR3, CD85a |
| Isotype | IgG2a |
| Species Reactivity | Human (Others untested) |
| Concentration | 1 mg/ml |
Stable for 12 months from date of receipt when stored at 4°C. Avoid repeated freeze-thaw cycles.
Leukocyte immunoglobulin-like receptor subfamily B member 3 (LILRB3) belongs to the immunoglobulin superfamily and is part of the LILR cluster located in the leukocyte receptor complex on chromosome 19. It is a transmembrane glycoprotein containing multiple extracellular immunoglobulin-like domains and intracellular immunoreceptor tyrosine-based inhibitory motifs (ITIMs), which enable it to recruit phosphatases and transmit inhibitory signals. LILRB3 is primarily expressed on myeloid cells and is involved in modulating immune responses by dampening cellular activation. Its specific ligands remain incompletely characterized.
