- Description
CSB VeRSaMAbs:
We produce and validate all our monoclonal antibodies in-house so that you can confidently choose the right antibody for your assay. All antibodies are VALIDATED for common applications, RECOMBINANT for batch-to-batch consistency, and SPECIFIC in binding to only your target.
| Target | IL6R |
| Target Aliases | Gp80, IL-1Ra, CD126, IL-6R, IL6RA, IL-6RA, IL-6R-1, IL-6R 1, IL6QTL, HIES5, IL6RQ, IL6Q |
| Isotype | IgG2a |
| Species Reactivity | Human (Others untested) |
| Concentration | 1 mg/ml |
Stable for 12 months from date of receipt when stored at 4°C. Avoid repeated freeze-thaw cycles.
IL6R is a single-pass transmembrane protein and part of the receptor for IL6. IL6R needs to associate with IL6ST to transduce a signal. The membrane-bound form of IL6R has primarily anti-inflammatory effects, while the soluble form of IL6R contributes to the pro-inflammatory effects of IL6. IL6R and IL6 are involved in multiple myeloma, autoimmune diseases, chronic inflammatory diseases, and prostate cancer.
