- Description
CSB VeRSaMAbs:
We produce and validate all our monoclonal antibodies in-house so that you can confidently choose the right antibody for your assay. All antibodies are VALIDATED for common applications, RECOMBINANT for batch-to-batch consistency, and SPECIFIC in binding to only your target.
| Target | HER2/ERBB2 |
| Target Aliases | ERBB2, NEU, CD340, NGL, MLN19, VSCN2, TKR1 |
| Isotype | IgG2a |
| Species Reactivity | Human (Others untested) |
| Concentration | 1 mg/ml |
Stable for 12 months from date of receipt when stored at 4°C. Avoid repeated freeze-thaw cycles.
HER2 is a single-pass transmembrane protein and member of the epidermal growth factor (EGF) receptor family. This tyrosine kinase receptor does not have a ligand-binding domain. Instead, HER2 stabilizes ligand binding and enhances activation of signaling pathways by forming a heterodimer with ligand-binding EGF receptor family members. HER2 regulates outgrowth and stabilization of peripheral microtubules and is overexpressed in multiple types of cancer, including breast and ovarian cancers.
