- Description
CSB VeRSaMAbs:
We produce and validate all our monoclonal antibodies in-house so that you can confidently choose the right antibody for your assay. All antibodies are VALIDATED for common applications, RECOMBINANT for batch-to-batch consistency, and SPECIFIC in binding to only your target.
| Target | EGFR |
| Target Aliases | ERBB1, ERRP, ERBB, HER1, EGFR VIII, NISBD2, PIG61, MENA |
| Isotype | IgG2a |
| Species Reactivity | Human (Others untested) |
| Concentration | 1 mg/ml |
Stable for 12 months from date of receipt when stored at 4°C. Avoid repeated freeze-thaw cycles.
EGFR is a single-pass transmembrane protein and member of the protein kinase superfamily that binds proteins in the epidermal growth factor family, causing receptor dimerization and tyrosine autophosphorylation, which activate signaling cascades. EGFR is involved in cell proliferation and migration and plays a role in hepatitis C infection and cytokine storm in severe COVID-19. Mutations in the EGFR gene are also associated with lung cancer.
