- Description
CSB VeRSaMAbs:
We produce and validate all our monoclonal antibodies in-house so that you can confidently choose the right antibody for your assay. All antibodies are VALIDATED for common applications, RECOMBINANT for batch-to-batch consistency, and SPECIFIC in binding to only your target.
| Target | Claudin-5 |
| Target Aliases | TMVCF, Claudin 5, CLDN5 |
| Isotype | IgG2a |
| Species Reactivity | Human (Others untested) |
| Concentration | 1 mg/ml |
Stable for 12 months from date of receipt when stored at 4°C. Avoid repeated freeze-thaw cycles.
Claudin-5 (CLDN5) is a member of the claudin family of integral membrane proteins, which are critical components of tight junction strands in epithelial and endothelial cells. CLDN5 is predominantly expressed in endothelial cells, especially within the blood-brain barrier, where it contributes to regulating paracellular permeability and maintaining vascular integrity. The protein spans the membrane four times and participates in cell–cell adhesion by forming tight junction complexes with other claudins. Its function is essential for the selective restriction of solutes across endothelial barriers.
