- Description
CSB VeRSaMAbs:
We produce and validate all our monoclonal antibodies in-house so that you can confidently choose the right antibody for your assay. All antibodies are VALIDATED for common applications, RECOMBINANT for batch-to-batch consistency, and SPECIFIC in binding to only your target.
| Target | Claudin-19 |
| Target Aliases | CLDN19, Claudin 19 |
| Isotype | IgG2a |
| Species Reactivity | Human (Others untested) |
| Concentration | 1 mg/ml |
Stable for 12 months from date of receipt when stored at 4°C. Avoid repeated freeze-thaw cycles.
Claudin 19 is a member of the claudin family of tetraspan integral membrane proteins that are core structural components of tight junction strands. The protein contains four transmembrane helices with cytoplasmic N- and C-termini and two extracellular loops that contribute to paracellular barrier properties and ion selectivity. CLDN19 localizes to tight junctions in epithelial cells and is expressed in kidney and ocular tissues. Expression data support enrichment in kidney and eye, consistent with its role in epithelial barrier function.
