- Description
CSB VeRSaMAbs:
We produce and validate all our monoclonal antibodies in-house so that you can confidently choose the right antibody for your assay. All antibodies are VALIDATED for common applications, RECOMBINANT for batch-to-batch consistency, and SPECIFIC in binding to only your target.
| Target | CD80 |
| Target Aliases | CD28LG1, CD28LG, B7.1, B7-1, LAB7, BB1, B7 |
| Isotype | IgG2a |
| Species Reactivity | Human (Others untested) |
| Concentration | 1 mg/ml |
Stable for 12 months from date of receipt when stored at 4°C. Avoid repeated freeze-thaw cycles.
CD80 is a single-pass transmembrane protein. CD80 can be activated by binding either CD28 or CTLA4, each resulting in different effects. When activated by CD28, CD80 induces T-cell proliferation and cytokine production. When activated by CTLA4, CD80 inhibits T-cell activation. CD80 is also an adenovirus subgroup B receptor and may be involved in lupus neuropathy.
