- Description
CSB VeRSaMAbs:
We produce and validate all our monoclonal antibodies in-house so that you can confidently choose the right antibody for your assay. All antibodies are VALIDATED for common applications, RECOMBINANT for batch-to-batch consistency, and SPECIFIC in binding to only your target.
| Target | CD53 |
| Target Aliases | TSPAN25, MOX44, AIM, Leukocyte surface antigen CD53 |
| Isotype | IgG2a |
| Species Reactivity | Human (Others untested) |
| Concentration | 1 mg/ml |
Stable for 12 months from date of receipt when stored at 4°C. Avoid repeated freeze-thaw cycles.
CD53 is a member of the tetraspanin protein family, defined by the presence of four transmembrane domains and a role in organizing membrane microdomains. It is expressed on a broad range of hematopoietic cells, including B cells, T cells, monocytes, macrophages, and granulocytes. CD53 contributes to cellular processes such as adhesion, migration, and immune cell activation by interacting with other surface proteins including integrins. While the precise molecular mechanisms are not fully resolved, its function is associated with the modulation of immune signaling pathways.
