- Description
CSB VeRSaMAbs:
We produce and validate all our monoclonal antibodies in-house so that you can confidently choose the right antibody for your assay. All antibodies are VALIDATED for common applications, RECOMBINANT for batch-to-batch consistency, and SPECIFIC in binding to only your target.
| Target | CD4 |
| Target Aliases | CD4mut, IMD79, OKT4D, T-Cell Surface Antigen T4/Leu-3 |
| Isotype | IgG2a |
| Species Reactivity | Human (Others untested) |
| Concentration | 1 mg/ml |
Stable for 12 months from date of receipt when stored at 4°C. Avoid repeated freeze-thaw cycles.
Cluster of differentiation 4 (CD4) is a type I transmembrane glycoprotein belonging to the immunoglobulin superfamily. It is primarily expressed on the surface of T helper lymphocytes, monocytes, macrophages, and dendritic cells, where it functions as a co-receptor that enhances T cell receptor signaling through interaction with major histocompatibility complex class II (MHC II) molecules. The extracellular region contains four immunoglobulin-like domains, while the cytoplasmic tail associates with the tyrosine kinase LCK to facilitate intracellular signaling. CD4 also serves as a receptor for the HIV-1 envelope glycoprotein gp120, enabling viral entry into host cells.
