- Description
CSB VeRSaMAbs:
We produce and validate all our monoclonal antibodies in-house so that you can confidently choose the right antibody for your assay. All antibodies are VALIDATED for common applications, RECOMBINANT for batch-to-batch consistency, and SPECIFIC in binding to only your target.
| Target | CD206 |
| Target Aliases | MRC1, Mannose Receptor C-Type 1, CLEC13DL, CLEC13D, BA541I19.1, MRC1L1, Macrophage Mannose Receptor 1-Like Protein 1 |
| Isotype | IgG2a |
| Species Reactivity | Human (Others untested) |
| Concentration | 1 mg/ml |
Stable for 12 months from date of receipt when stored at 4°C. Avoid repeated freeze-thaw cycles.
CD206 or Macrophage mannose receptor 1 is a type I transmembrane glycoprotein belonging to the C-type lectin receptor family. The protein contains an N-terminal cysteine-rich domain, a fibronectin type II domain, multiple C-type lectin-like domains, a single transmembrane helix, and a short cytoplasmic tail. CD206 mediates calcium-dependent recognition and endocytosis of glycoproteins bearing terminal mannose, fucose, or N-acetylglucosamine residues and contributes to pathogen uptake and clearance. The receptor is primarily expressed on macrophages and dendritic cells and localizes to the plasma membrane and endosomal compartments.
