- Description
CSB VeRSaMAbs:
We produce and validate all our monoclonal antibodies in-house so that you can confidently choose the right antibody for your assay. All antibodies are VALIDATED for common applications, RECOMBINANT for batch-to-batch consistency, and SPECIFIC in binding to only your target.
| Target | CD16 |
| Target Aliases | CD16a: FGCR3A, Fc Gamma Receptor IIIa, FcgammaRIIIa, FcGRIIIA, CD16a, FCGR3, CD16 CD16b: FCGR3B, Fc Gamma Receptor IIIb, FcRIIIb, FcgammaRIIIb, CD16b, FCGR3, CD16, FCG3 |
| Isotype | IgG2a |
| Species Reactivity | Human (Others untested) |
| Concentration | 1 mg/ml |
Stable for 12 months from date of receipt when stored at 4°C. Avoid repeated freeze-thaw cycles.
CD16 refers to two closely related receptors, FCGR3A and FCGR3B, both members of the immunoglobulin superfamily that bind the Fc portion of IgG antibodies with low affinity. These proteins contain extracellular immunoglobulin-like domains and differ in their membrane anchoring: FCGR3A is a transmembrane protein expressed on natural killer (NK) cells, macrophages, and subsets of T cells, while FCGR3B is GPI-anchored and primarily found on neutrophils. CD16 mediates antibody-dependent cellular cytotoxicity (ADCC) and other immune effector functions through IgG binding. These receptors play a central role in linking the adaptive humoral response to innate immune mechanisms.
