- Description
| Specificity Profile | More Information |
 | The specificity of SLC3A2 Monoclonal Antibody (CSB0057) was tested on the Membrane Proteome Array™ and shown to be specific for human SLC3A2. The Membrane Proteome Array™ contains 6,000 different human membrane proteins, each expressed in unfixed avian cells to ensure native conformation and post-translational modifications. The Membrane Proteome Array™ represents the industry standard for determining the binding specificity of antibodies and other protein ligands. |
| Application | Conditions | Recommended Concentration |
| Flow Cytometry, Extracellular | Live, Unpermeabilized | 1 µg/ml |
 | JS-1 cells transiently transfected with human SLC3A2 were stained with SLC3A2 Monoclonal Antibody (CSB0057) (green) or isotype control antibody (gray), followed by AlexaFluor 647-conjugated anti-Mouse IgG secondary antibody. JS-1 cells transiently transfected with an empty control vector were also stained with SLC3A2 Monoclonal Antibody (CSB0057) (blue). | |
| Application | Conditions | Recommended Concentration |
| Immunofluorescence, Extracellular | Fixed 4% paraformaldehyde | 1 µg/ml |
 | (A) JS-1 cells transiently transfected with human SLC3A2 were stained with SLC3A2 Monoclonal Antibody (CSB0057) followed by AlexaFluor 647 anti-Mouse IgG secondary antibody (red) and DAPI (blue). (B) JS-1 cells transiently transfected with an empty control vector stained with SLC3A2 Monoclonal Antibody. (C) Isotype control: JS-1 cells transfected with human SLC3A2 and stained with control MAb. | |
| Application | Conditions | Recommended Concentration |
| Immunofluorescence, Intracellular | Fixed 4% paraformaldehyde, Permeabilized 0.1% Triton X-100 | 1 µg/ml |
 | (A) JS-1 cells transiently transfected with human SLC3A2 were permeabilized and stained with SLC3A2 Monoclonal Antibody (CSB0057) followed by AlexaFluor 647 anti-Mouse IgG secondary antibody (red) and DAPI (blue). (B) JS-1 cells transiently transfected with an empty control vector stained with SLC3A2 Monoclonal Antibody. (C) Isotype control: JS-1 cells transfected with human SLC3A2 and stained with control MAb. | |
CSB VeRSaMAbs:
We produce and validate all our monoclonal antibodies in-house so that you can confidently choose the right antibody for your assay. All antibodies are VALIDATED for common applications, RECOMBINANT for batch-to-batch consistency, and SPECIFIC in binding to only your target.
| Target | SLC3A2 |
| Target Aliases | CD98HC, 4T2HC, NACAE, 4F2HC, CD98, MDU1, 4F2, 4F2hc |
| Isotype | Mouse IgG2a |
| Membrane Proteome Specificity | Monospecific for 6,000 membrane proteins tested |
| Species Reactivity | Human (others untested) |
| Fc Modifications | C-terminal Avitag, disabled Fc-gamma receptor binding |
| Source | Recombinant CHO expression; purified by Protein A chromatography |
| Formulation | Endotoxin Free PBS pH 7.4, sterile-filtered |
| Concentration | 1 mg/ml |
Stable for 12 months from date of receipt when stored at 4°C. Avoid repeated freeze-thaw cycles.
SLC3A2 is a single-pass transmembrane protein that is part of the solute carrier family. SLC3A2 forms a homodimer as well as heterodimers with several other proteins, including SLC7A6, SLC7A7, SLC7A5, and SLC7A8. The homodimer and heterodimers are amino acid transporters with differing substrates. SLC3A2 also regulates intracellular Ca2+ levels. The heterodimer with SLC7A5 facilitates viral entry of hepatitis C. (NCBI Gene: 6520, UniProtKB/Swiss-Prot: P08195). Other names: CD98HC, 4T2HC, NACAE, 4F2HC, CD98, MDU1, 4F2, 4F2hc
